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CS-W001157 4
Total: USD 88.00

1-Methyl-1H-indazole-3-carboxylic acid

  • CAS No. 50890-83-0

  • Cat. No. CS-W007927
  • Purity≥98%
  • MDL No.MFCD00272569

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-indazole-3-carboxylic acid|CS-W007927

Structure of 50890-83-0

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General Information

  • CAS No. 50890-83-0
  • Cat. No. CS-W007927
  • Purity ≥98%
  • MDL No. MFCD00272569
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O₂
  • Molecular Weight 176.17
  • Synonym(s) None
  • SMILES C1=CC=CC2=C1C(=N[N]2C)C(O)=O

Description

Cortisone is a corticosteroid produced in the adrenal glands. Cortisone is administered for short term pain relief and to reduce swelling from inflammation. This Certified Spiking Solution is applicable in LC-MS/MS applications for endocrinology, clinical chemistry and neonatal screening.

Application

1-Methyl-1H-indazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its carboxylic acid functionality facilitates amide coupling, esterification, and metal-catalyzed transformations under standard conditions. The molecule exhibits good bench stability and functional group tolerance, supporting its use in multi-step synthesis of kinase inhibitors and other targeted therapeutics.

Synthesis

  • Route1
    • In-stock
      Indazole-3-carboxylic acid|CS-W002518
      4498-67-3
    • null|null
      77-78-1
    • ~86%
    • In-stock
      1-Methyl-1H-indazole-3-carboxylic acid|CS-W007927
      50890-83-0

    References

    • Chemagis Ltd. Patent: EP1484321 A1, 2004 ; Location in patent: Page 7 ;
  • Route2
    • In-stock
      Indazole-3-carboxylic acid|CS-W002518
      4498-67-3
    • null|null
      74-88-4
    • ~85%
    • In-stock
      1-Methyl-1H-indazole-3-carboxylic acid|CS-W007927
      50890-83-0

    References

    • Chemagis Ltd. Patent: EP1484321 A1, 2004 ; Location in patent: Page 7 ;
  • Route3

    References

    • Chemagis Ltd. Patent: EP1484321 A1, 2004 ; Location in patent: Page 8-9 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   1.2715
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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