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CS-W001157 4
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(βS)-β-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-thiophenepropanoic acid

  • CAS No. 507472-08-4

  • Cat. No. CS-0654406
  • Molecule weight393.46
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(βS)-β-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-thiophenepropanoic acid|CS-0654406

Structure of 507472-08-4

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General Information

  • CAS No. 507472-08-4
  • Cat. No. CS-0654406
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₁₉NO₄S
  • Molecular Weight 393.46
  • Synonym(s) None
  • SMILES OC(C[C@@H](C1=CC=CS1)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O

Description

This fluorenylmethoxycarbonyl-protected thiophene-containing amino acid features a bench-stable, moisture-tolerant side chain ideal for peptide synthesis. The β-thiophenepropanoic acid scaffold integrates readily into peptide backbones, while the Fmoc group enables orthogonal deprotection. This derivative supports efficient solid-phase and solution-phase coupling protocols.

Application

(βS)-β-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-thiophenepropanoic acid serves as a chiral building block for peptide synthesis, enabling the incorporation of thiophene-containing amino acids with defined stereochemistry. The Fmoc group provides orthogonal protection and facilitates efficient removal under mild basic conditions. Its stability, compatibility with standard coupling reagents, and ease of purification make it ideal for solid-phase and solution-phase peptide assembly workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.8026
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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