Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Methoxyisoindoline-1,3-dione

  • CAS No. 50727-04-3

  • Cat. No. CS-0038558
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Methoxyisoindoline-1,3-dione|CS-0038558

Structure of 50727-04-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 50727-04-3
  • Cat. No. CS-0038558
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NO₃
  • Molecular Weight 177.16
  • Synonym(s) 5-methoxyisoindole-1,3-dione
  • SMILES COC1=CC2=C(C=C1)C(=NC2=O)O

Description

5-Methoxyisoindoline-1,3-dione features a methoxy-substituted isoindoline-1,3-dione core with enhanced solubility and stability under standard bench conditions. This electron-deficient scaffold integrates readily into heterocyclic syntheses, serving as a key building block for bioactive molecules in medicinal chemistry.

Application

5-Methoxyisoindoline-1,3-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted isoindolinones and related heterocyclic scaffolds. Its methoxy group enhances solubility and modulates reactivity, while the electron-deficient dione core facilitates nucleophilic addition and cycloaddition reactions. The compound exhibits bench stability and compatibility with common functional groups, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • ASTEX THERAPEUTICS LIMITED Patent: WO2008/44045 A1, 2008 ; Location in patent: Page/Page column 277-278 ; WO 2008/044045 A1
  • Route2

    References

    • Mazzocchi, P. H.; Wilson, P.; Khachik, F.; Klingler, L.; Minamikawa, S. Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 2981 - 2989
  • Route3

    References

    • Hennige, Hans; Kreher, Richard P.; Konrad, Michael; Jelitto, Frank Chemische Berichte, 1988 , vol. 121, p. 243 - 252

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   58.89
  • LogP   1.1536
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Methoxyisoindoline-1,3-dione sigma5-Methoxyisoindoline-1,3-dione manufacturer5-Methoxyisoindoline-1,3-dione price5-Methoxyisoindoline-1,3-dione structure5-Methoxyisoindoline-1,3-dione SDSbuy 5-Methoxyisoindoline-1,3-dione5-Methoxyisoindoline-1,3-dione supplier5-Methoxyisoindoline-1,3-dione uses5-Methoxyisoindoline-1,3-dione molecular weightprice of 5-Methoxyisoindoline-1,3-dione5-Methoxyisoindoline-1,3-dione chemical name formula of 5-Methoxyisoindoline-1,3-dione
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label