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CS-W001157 4
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Silver(I) dibenzyl phosphate

  • CAS No. 50651-75-7

  • Cat. No. CS-0156143
  • Purity≥97%
  • MDL No.MFCD00067264

*For research and further manufacturing use only, not for direct human use.

Silver(I) dibenzyl phosphate|CS-0156143

Structure of 50651-75-7

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General Information

  • CAS No. 50651-75-7
  • Cat. No. CS-0156143
  • Purity ≥97%
  • MDL No. MFCD00067264
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₄AgO₄P
  • Molecular Weight 385.10
  • Synonym(s) Silver dibenzyl phosphate
  • SMILES C1=CC=C(C=C1)COP(=O)([O-])OCC2=CC=CC=C2.[Ag+]

Description

Silver(I) dibenzyl phosphate offers a stable, moisture-tolerant source of Ag⁺ for coordination chemistry and catalysis. The dibenzyl phosphate ligand enhances solubility in organic media while maintaining reactivity under standard bench conditions. This complex integrates readily into transition-metal-mediated transformations and serves as a reliable precursor for silver-catalyzed C–H functionalization and coupling reactions.

Application

Silver(I) dibenzyl phosphate serves as a reliable source of Ag⁺ for catalytic transformations, particularly in C–H functionalization and coupling reactions. Its stability under inert conditions and compatibility with diverse functional groups enable efficient activation of substrates in synthetic workflows. The reagent facilitates selective phosphoesterification and functions as a mild, bench-stable silver source in heterocycle synthesis and cross-coupling protocols.

Synthesis

  • Route1

    References

    • KEMPHARM INC.; GUENTHER, Sven; CHI, Guochen; BERA, Bindu; MICKLE, Travis Patent: WO2013/16668 A2, 2013 ; Location in patent: Paragraph 00249; 00250 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.59
  • LogP   2.8859
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   6

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