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CS-W001157 4
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6-methoxybenzofuran-2-carboxylic acid

  • CAS No. 50551-61-6

  • Cat. No. CS-0062580
  • Purity≥98%
  • MDL No.MFCD06254721

*For research and further manufacturing use only, not for direct human use.

6-methoxybenzofuran-2-carboxylic acid|CS-0062580

Structure of 50551-61-6

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General Information

  • CAS No. 50551-61-6
  • Cat. No. CS-0062580
  • Purity ≥98%
  • MDL No. MFCD06254721
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈O₄
  • Molecular Weight 192.17
  • Synonym(s) 6-METHOXY-BENZOFURAN-2-CARBOXYLIC ACID
  • SMILES O=C(O)C1=CC2=CC=C(OC)C=C2O1

Description

6-Methoxybenzofuran-2-carboxylic acid features a fused benzofuran core with a methoxy group at the 6-position and a carboxylic acid at the 2-position. This combination imparts enhanced solubility and electronic modulation, enabling direct incorporation into pharmaceutical scaffolds. The molecule exhibits bench-stable handling properties and serves as a key building block for bioactive heterocycles in medicinal chemistry applications.

Application

6-Methoxybenzofuran-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocyclic scaffolds. Its ortho-substituted benzofuran core offers enhanced metabolic stability and tunable solubility, while the carboxylic acid group facilitates direct coupling reactions or derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in standard peptide coupling, esterification, and amide formation protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.67
  • LogP   2.1396
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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