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CS-W001157 4
Total: USD 88.00

2-(4-(Trifluoromethyl)phenoxy)acetic acid

  • CAS No. 163839-73-4

  • Cat. No. CS-0157430
  • Molecule weight220.15
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-(Trifluoromethyl)phenoxy)acetic acid|CS-0157430

Structure of 163839-73-4

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General Information

  • CAS No. 163839-73-4
  • Cat. No. CS-0157430
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇F₃O₃
  • Molecular Weight 220.15
  • Synonym(s) None
  • SMILES C1=C(C=CC(=C1)OCC(=O)O)C(F)(F)F

Description

This trifluoromethyl-substituted phenolic acetic acid delivers enhanced lipophilicity and metabolic stability, making it a valuable scaffold in medicinal chemistry. The electron-withdrawing trifluoromethyl group modulates acidity and influences binding affinity in bioactive molecules. Its robust functionality enables straightforward derivatization for drug discovery applications.

Application

2-(4-(Trifluoromethyl)phenoxy)acetic acid serves as a versatile building block for constructing bioactive molecules, enabling efficient incorporation of a trifluoromethyl-substituted aryl ether motif. Its stability and compatibility with standard coupling reactions facilitate synthesis of pharmaceutical intermediates and functional materials.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.1688
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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