Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromo-1-(4-(methylsulfonyl)phenyl)ethanone

  • CAS No. 50413-24-6

  • Cat. No. CS-0186566
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1-(4-(methylsulfonyl)phenyl)ethanone|CS-0186566

Structure of 50413-24-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 50413-24-6
  • Cat. No. CS-0186566
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉BrO₃S
  • Molecular Weight 277.13
  • Synonym(s) 2-bromo-1-[4-(methylsulfonyl)phenyl]ethanone
  • SMILES CS(=O)(=O)C1=CC=C(C=C1)C(=O)CBr

Description

2-Bromo-1-(4-(methylsulfonyl)phenyl)ethanone is a brominated aryl ketone featuring a methylsulfonyl group that enhances solubility and stability. This compound serves as a key intermediate in the synthesis of biologically active molecules, particularly in pharmaceutical development where its electrophilic bromine facilitates C–C coupling reactions under mild conditions.

Application

2-Bromo-1-(4-(methylsulfonyl)phenyl)ethanone serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality. The methylsulfonyl group enhances solubility and provides orthogonal reactivity, while the ketone moiety supports further transformations such as enolization or nucleophilic addition. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for constructing complex scaffolds in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • EP912537 B1, ; Page 8-9 ;
  • Route2

    References

    • EP1246825 B1, ; Page 25 ;
  • Route3

    References

    • Synthesis, , # 12 p. 1778 - 1779

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS08
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302+H312+H332-H314-H341
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.21
  • LogP   1.6677
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 50413-24-6 sigma50413-24-6 manufacturer50413-24-6 price50413-24-6 structure50413-24-6 SDSbuy 50413-24-650413-24-6 supplier50413-24-6 uses50413-24-6 molecular weightprice of 50413-24-650413-24-6 chemical name formula of 50413-24-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label