Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4'-(Methylsulfonyl)acetophenone

  • CAS No. 10297-73-1

  • Cat. No. CS-D1688
  • Purity≥98%
  • MDL No.MFCD00025072

*For research and further manufacturing use only, not for direct human use.

4'-(Methylsulfonyl)acetophenone|CS-D1688

Structure of 10297-73-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 10297-73-1
  • Cat. No. CS-D1688
  • Purity ≥98%
  • MDL No. MFCD00025072
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃S
  • Molecular Weight None
  • Synonym(s) None
  • SMILES CC(C1=CC=C(S(=O)(C)=O)C=C1)=O

Description

4'-(Methylsulfonyl)acetophenone features a para-methylsulfonyl group that enhances solubility and metabolic stability, while the acetyl functionality enables direct electrophilic coupling in cross-coupling reactions. This bench-stable compound integrates readily into pharmaceutical intermediates and functional materials synthesis under standard conditions.

Application

4'-(Methylsulfonyl)acetophenone serves as a versatile building block in medicinal chemistry, enabling efficient construction of biologically active scaffolds. The methylsulfonyl group enhances solubility and metabolic stability, while the ketone functionality supports nucleophilic addition, enolate formation, and coupling reactions. Its bench-stable nature and compatibility with standard transformations make it ideal for modular synthesis workflows.

Synthesis

  • Route1

    References

    • Therien; Yves Gauthier; Leblanc; Leger; Perrier; Prasit; Wang Synthesis, 2001 , # 12 p. 1778 - 1779
  • Route2
    • In-stock
      1-(4-Methanesulfonylphenyl)ethan-1-ol|CS-0161927
      25888-99-7
    • ~29%
    • In-stock
      4'-(Methylsulfonyl)acetophenone|CS-D1688
      10297-73-1
    • 4-Methylsulphonylbenzoic acid Etoricoxib  Impurity|CS-0229443
      4052-30-6

    References

    • Tetrahedron, , vol. 67, # 19 p. 3406 - 3411
  • Route3

    References

    • Zhu, Wei; Ma, Dawei Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2696 - 2700

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.21
  • LogP   1.2927
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4'-(Methylsulfonyl)acetophenone sigma4'-(Methylsulfonyl)acetophenone manufacturer4'-(Methylsulfonyl)acetophenone price4'-(Methylsulfonyl)acetophenone structure4'-(Methylsulfonyl)acetophenone SDSbuy 4'-(Methylsulfonyl)acetophenone4'-(Methylsulfonyl)acetophenone supplier4'-(Methylsulfonyl)acetophenone uses4'-(Methylsulfonyl)acetophenone molecular weightprice of 4'-(Methylsulfonyl)acetophenone4'-(Methylsulfonyl)acetophenone chemical name formula of 4'-(Methylsulfonyl)acetophenone
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label