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CS-W001157 4
Total: USD 88.00

4-Hydroxyoxane-4-carboxylic acid

  • CAS No. 50289-13-9

  • Cat. No. CS-0050835
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Hydroxyoxane-4-carboxylic acid|CS-0050835

Structure of 50289-13-9

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General Information

  • CAS No. 50289-13-9
  • Cat. No. CS-0050835
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₄
  • Molecular Weight 146.14
  • Synonym(s) 4-Hydroxytetrahydropyran-4-carboxylic Acid
  • SMILES OC(=O)C1(O)CCOCC1

Description

4-Hydroxyoxane-4-carboxylic acid features a hydroxyl group at the C4 position of a saturated oxane ring, combined with a carboxylic acid moiety at the same site. This unique bifunctional architecture enables direct incorporation into synthetic routes requiring both polar and reactive handles. The molecule exhibits enhanced solubility in aqueous and protic solvents, facilitating use under standard bench conditions. Its stability supports reliable handling in multi-step syntheses.

Application

4-Hydroxyoxane-4-carboxylic acid serves as a versatile building block for heterocyclic synthesis, particularly in the construction of oxane and oxepane scaffolds. Its bifunctional nature—combining a hydroxyl and carboxylic acid group at C4—enables controlled derivatization, including esterification and lactonization, under standard conditions. The compound exhibits good bench stability and facilitates efficient functional group manipulations in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   -0.3875
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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