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CS-W001157 4
Total: USD 88.00

2-((Benzylamino)methyl)phenol

  • CAS No. 5001-26-3

  • Cat. No. CS-0528515
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-((Benzylamino)methyl)phenol|CS-0528515

Structure of 5001-26-3

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General Information

  • CAS No. 5001-26-3
  • Cat. No. CS-0528515
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₅NO
  • Molecular Weight 213.28
  • Synonym(s) N-benzyl-o-hydroxybenzylamine
  • SMILES OC1=CC=CC=C1CNCC2=CC=CC=C2

Description

This benzylamine-substituted phenol features a strategically positioned amine-alkyl linker that enhances solubility and reactivity in synthetic transformations. The ortho-hydroxyl group enables coordination to metal catalysts, while the benzylamino methyl moiety provides a handle for further derivatization. Bench-stable under standard conditions, it integrates seamlessly into multistep synthesis workflows.

Application

2-((Benzylamino)methyl)phenol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard condensation and cyclization protocols. Its pendant benzylamine and phenolic functionalities offer orthogonal reactivity for selective derivatization, while the molecule exhibits robust bench stability and straightforward purification—facilitating integration into multi-step synthetic sequences for API development.

Safety Information

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   2.682
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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