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CS-W001157 4
Total: USD 88.00

2,3,5-Trichlorobenzoic acid

  • CAS No. 50-73-7

  • Cat. No. CS-0157739
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3,5-Trichlorobenzoic acid|CS-0157739

Structure of 50-73-7

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General Information

  • CAS No. 50-73-7
  • Cat. No. CS-0157739
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃Cl₃O₂
  • Molecular Weight 225.46
  • Synonym(s) Benzoic acid, 2,3,5-trichloro-
  • SMILES C1=C(C=C(C(=C1C(=O)O)Cl)Cl)Cl

Description

2,3,5-Trichlorobenzoic acid is a highly chlorinated aromatic carboxylic acid featuring three chlorine substituents at the 2, 3, and 5 positions of the benzene ring. This electron-deficient scaffold enables efficient coupling in electrophilic functionalization and serves as a robust building block for advanced synthetic intermediates. The molecule exhibits enhanced stability under standard bench conditions and integrates readily into complex molecular architectures requiring halogen-directed reactivity.

Application

2,3,5-Trichlorobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering high functional group tolerance and enhanced metabolic stability due to its electron-withdrawing trichloro substitution. Its carboxylic acid functionality enables straightforward derivatization via esterification, amide coupling, or direct salt formation, facilitating downstream conjugation and purification. The compound exhibits excellent bench stability and is compatible with standard reaction conditions across diverse synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   3.345
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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