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CS-W001157 4
Total: USD 88.00

(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)boronic acid

  • CAS No. 499769-88-9

  • Cat. No. CS-W006840
  • Purity≥98%
  • MDL No.MFCD03095151

*For research and further manufacturing use only, not for direct human use.

(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)boronic acid|CS-W006840

Structure of 499769-88-9

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General Information

  • CAS No. 499769-88-9
  • Cat. No. CS-W006840
  • Purity ≥98%
  • MDL No. MFCD03095151
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BO₄
  • Molecular Weight 179.97
  • Synonym(s) Boronic acid, (2,3-dihydro-1,4-benzodioxin-5-yl)- (9CI)
  • SMILES OB(C1=C2C(OCCO2)=CC=C1)O

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering high yields under standard conditions. The dihydrobenzodioxin scaffold imparts exceptional stability and solubility in polar solvents, enabling efficient incorporation into complex molecular architectures.

Application

(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The dihydrobenzodioxin moiety imparts excellent bench stability and favorable solubility, while the boronic acid functionality exhibits broad functional group tolerance. It functions reliably in the synthesis of biaryl architectures relevant to medicinal chemistry and materials science, offering predictable reactivity and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   -0.8624
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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