Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Bromobenzenesulfonyl fluoride

  • CAS No. 498-83-9

  • Cat. No. CS-0132897
  • Purity≥95%
  • MDL No.MFCD21892326

*For research and further manufacturing use only, not for direct human use.

4-Bromobenzenesulfonyl fluoride|CS-0132897

Structure of 498-83-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 498-83-9
  • Cat. No. CS-0132897
  • Purity ≥95%
  • MDL No. MFCD21892326
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BrFO₂S
  • Molecular Weight 239.06
  • Synonym(s) AOXWZFUBFROIHA-UHFFFAOYSA-N
  • SMILES O=S(C1=CC=C(Br)C=C1)(F)=O

Description

4-Bromobenzenesulfonyl fluoride is a bench-stable, moisture-tolerant electrophile featuring a sulfonyl fluoride group flanked by a bromine-substituted aromatic ring. This combination enables selective coupling in synthetic transformations, particularly in the installation of sulfonamide functionalities under mild conditions.

Application

4-Bromobenzenesulfonyl fluoride serves as a versatile electrophilic sulfonylating agent, enabling efficient introduction of the sulfonamide moiety in medicinal chemistry and agrochemical synthesis. Its stability under ambient conditions and compatibility with diverse nucleophiles—particularly amines and alcohols—facilitates straightforward functionalization. The bromo substituent provides a handle for subsequent cross-coupling reactions, enhancing its utility in constructing complex molecular architectures.

Synthesis

  • Route1
    • null|null
      98-58-8
    • ~73%
    • In-stock
      4-Bromobenzenesulfonyl fluoride|CS-0132897
      498-83-9

    References

    • PROYECTO DE BIOMEDICINA CIMA, S.L.; ORBE LOPATEGUI, Josune; OYARZABAL SANTAMARINA, Julen; PÁRAMO FERNÁNDEZ, José Antonio; RODRÍGUEZ GARCÍA, José Antonio Patent: WO2014/12964 A1, 2014 ; Location in patent: Page/Page column 49 ;
  • Route2
    • null|null
      1156-18-9
    • ~37%
    • null|null
      153170-87-7
    • In-stock
      4-Bromobenzenesulfonyl fluoride|CS-0132897
      498-83-9
    • null|null
      1355251-13-6

    References

    • Yang, Xianjin; Chen, Guanlong; Chen, Fuli; Zhang, Yan; Yang, Xueyan; Yuan, Xiaoming; Wu, Fanhong Journal of Fluorine Chemistry, 2012 , vol. 133, p. 155 - 159
  • Route3
    • null|null
      108-86-1
    • ~3%
    • In-stock
      4-Bromobenzenesulfonyl fluoride|CS-0132897
      498-83-9
    • In-stock
      4,4'-Sulfonylbis(bromobenzene)|CS-W009758
      2050-48-8
    • null|null
      141223-29-2
    • null|null
      141223-30-5

    References

    • Tanaka, Mutsuo; Souma, Yoshie Journal of Organic Chemistry, 1992 , vol. 57, # 13 p. 3738 - 3740

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   34.14
  • LogP   2.1073
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Bromobenzenesulfonyl fluoride sigma4-Bromobenzenesulfonyl fluoride manufacturer4-Bromobenzenesulfonyl fluoride price4-Bromobenzenesulfonyl fluoride structure4-Bromobenzenesulfonyl fluoride SDSbuy 4-Bromobenzenesulfonyl fluoride4-Bromobenzenesulfonyl fluoride supplier4-Bromobenzenesulfonyl fluoride uses4-Bromobenzenesulfonyl fluoride molecular weightprice of 4-Bromobenzenesulfonyl fluoride4-Bromobenzenesulfonyl fluoride chemical name formula of 4-Bromobenzenesulfonyl fluoride
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label