Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Hydroxy-2-pyrone

  • CAS No. 496-64-0

  • Cat. No. CS-W021933
  • Purity≥95%
  • MDL No.MFCD01318559

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-2-pyrone|CS-W021933

Structure of 496-64-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 496-64-0
  • Cat. No. CS-W021933
  • Purity ≥95%
  • MDL No. MFCD01318559
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄O₃
  • Molecular Weight 112.08
  • Synonym(s) None
  • SMILES O=C1OC=CC=C1O

Description

3-Hydroxy-2H-pyran-2-one features a conjugated enone system flanked by a hydroxyl group, enabling facile participation in nucleophilic addition and cyclization reactions. This scaffold integrates readily into complex molecular architectures, serving as a key building block for natural product synthesis and functionalized heterocycles under mild conditions.

Application

3-Hydroxy-2H-pyran-2-one serves as a versatile building block in synthetic organic chemistry, enabling efficient access to bioactive heterocyclic scaffolds. Its enolizable carbonyl and hydroxyl functionalities facilitate diverse transformations, including aldol reactions, Michael additions, and cyclizations. The compound exhibits bench stability and mild reactivity, supporting straightforward purification and integration into multi-step syntheses. It functions effectively in the construction of polyfunctionalized pyran rings relevant to natural product and medicinal chemistry applications.

Synthesis

  • Route1

    References

    • Frebault, Frederic; Oliveira, Maria Teresa; Woestefeld, Eckhard; Maulide, Nuno Journal of Organic Chemistry, 2010 , vol. 75, # 22 p. 7962 - 7965
  • Route2
    • Vitamin C solution|CS-1692914
      50-81-7
    • ~%
    • In-stock
      3-Hydroxy-2-pyrone|CS-W021933
      496-64-0

    References

    • Obata, Hitoshi; Tanigaki, Hiroshi; Tanishita, Jun-ichi; Tokuyama, Tai Agricultural and Biological Chemistry, 1983 , vol. 47, # 2 p. 419 - 420
  • Route3

    References

    • Sakamaki, Kensuke; Ishizaki, Susumu; Ohkubo, Yasutaka; Tateno, Yoshiyuki; Nakanishi, Akira; Fujita, Akira Journal of Agricultural and Food Chemistry, 2012 , vol. 60, # 40 p. 9967 - 9973,7

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H316-H319-H335
Precautionary Statements : P332+P313-P264-P280-P305+P351+P338-P337+P313-P280-P302+P352-P362+P364

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.44
  • LogP   0.3454
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Hydroxy-2-pyrone sigma3-Hydroxy-2-pyrone manufacturer3-Hydroxy-2-pyrone price3-Hydroxy-2-pyrone structure3-Hydroxy-2-pyrone SDSbuy 3-Hydroxy-2-pyrone3-Hydroxy-2-pyrone supplier3-Hydroxy-2-pyrone uses3-Hydroxy-2-pyrone molecular weightprice of 3-Hydroxy-2-pyrone3-Hydroxy-2-pyrone chemical name formula of 3-Hydroxy-2-pyrone
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label