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CS-W001157 4
Total: USD 88.00

USF 2550A

  • CAS No. 5192-62-1

  • Cat. No. CS-0513709
  • Purity≥98%
  • MDL No.MFCD00090424

*For research and further manufacturing use only, not for direct human use.

USF 2550A|CS-0513709

Structure of 5192-62-1

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General Information

  • CAS No. 5192-62-1
  • Cat. No. CS-0513709
  • Purity ≥98%
  • MDL No. MFCD00090424
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈O₃
  • Molecular Weight 140.14
  • Synonym(s) None
  • SMILES O=C1C(C)=C(O)C=C(C)O1

Description

Acid-PEG1-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Synthesis

  • Route1
    • null|null
      58273-06-6
    • ~64%
    • USF 2550A|CS-0513709
      5192-62-1

    References

    • Ziegler, Erich; Wolfbeis, Otto S.; Trummer, Iris Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1982 , vol. 37, # 1 p. 105 - 107
  • Route2
    • null|null
      94632-42-5
    • ~81%
    • USF 2550A|CS-0513709
      5192-62-1

    References

    • Oikawa, Hideaki; Kobayashi, Tomonori; Katayama, Kinya; Suzuki, Yuichi; Ichihara, Akitami Journal of Organic Chemistry, 1998 , vol. 63, # 24 p. 8748 - 8756
  • Route3
    • null|null
      92925-21-8
    • ~62%
    • USF 2550A|CS-0513709
      5192-62-1

    References

    • Moreno-Manas, Marcial; Pleixats, Roser Synthesis, 1984 , # 5 p. 430 - 431

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.44
  • LogP   0.96224
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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