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Structure of 490039-83-3
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2-Iodo-4-methoxybenzonitrile features a reactive iodine atom and a nitrile group flanked by a methoxy substituent, enabling efficient coupling in cross-coupling reactions. This electron-deficient aryl halide delivers high functional group tolerance and stability under standard conditions, facilitating the synthesis of complex aromatic scaffolds in medicinal chemistry and materials science applications.
2-Iodo-4-methoxybenzonitrile serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of biaryl and heteroaryl scaffolds. The iodine group facilitates reliable palladium-catalyzed coupling reactions, while the methoxy and nitrile functionalities offer orthogonal handles for further derivatization. Bench-stable and readily purified, it functions effectively in Suzuki, Stille, and Negishi transformations, supporting scalable synthesis of pharmaceutical intermediates and functional materials.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: