Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Bromomethyl-2(1H)-quinolinone

  • CAS No. 4876-10-2

  • Cat. No. CS-M3370
  • Purity≥95%
  • MDL No.MFCD03426152

*For research and further manufacturing use only, not for direct human use.

4-Bromomethyl-2(1H)-quinolinone|CS-M3370

Structure of 4876-10-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 4876-10-2
  • Cat. No. CS-M3370
  • Purity ≥95%
  • MDL No. MFCD03426152
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrNO
  • Molecular Weight 238.08
  • Synonym(s) Carbostyril, 4-(bromomethyl)- (6CI,7CI); 4-(Bromomethyl)carbostyril; 4-(Bromomethyl)quinolin-2(1H)-one; 4-Bromomethyl-1H-quinolin-2-one; NSC 108455; 4-Bromomethyl-1,2-dihydroquinoline-2-one
  • SMILES O=C1NC2=C(C=CC=C2)C(CBr)=C1

Description

4-Bromomethyl-2(1H)-quinolinone features a bromomethyl group at the 4-position of a quinolinone scaffold, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. This bench-stable derivative integrates readily into complex molecular architectures, offering high reactivity with minimal side-product formation under standard conditions.

Application

4-Bromomethyl-2(1H)-quinolinone serves as a versatile synthetic building block for the construction of quinolinone-based scaffolds. The bromomethyl group enables efficient nucleophilic substitution and transition-metal-catalyzed coupling reactions, facilitating the installation of diverse side chains. Its stability under standard reaction conditions and compatibility with common functional groups make it well-suited for medicinal chemistry campaigns and process-scale synthesis.

Synthesis

  • Route1
    • Acetoacetanilide, 4-bromo-|CS-0018561
      1205-74-9
    • ~%
    • In-stock
      4-Bromomethyl-2(1H)-quinolinone|CS-M3370
      4876-10-2

    References

    • Journal of the Chemical Society, , vol. 97, p. 1981 Justus Liebigs Annalen der Chemie, , vol. 236, p. 70 Anm. Justus Liebigs Annalen der Chemie, , vol. 245, p. 357,368
  • Route2

    References

    • Pharmaceutical Bulletin, , vol. 1, p. 50 Chem.Abstr., , p. 12470
  • Route3
    • 4-Bromomethyl-2-chloroquinoline|CS-0713347
      137354-54-2
    • ~%
    • In-stock
      4-Bromomethyl-2(1H)-quinolinone|CS-M3370
      4876-10-2

    References

    • Pharmaceutical Bulletin, , vol. 1, p. 50 Chem.Abstr., , p. 12470

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P264-P271-P280-P301+P330+P331-P304+P340-P363-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   32.86
  • LogP   2.423
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Bromomethyl-2(1H)-quinolinone sigma4-Bromomethyl-2(1H)-quinolinone manufacturer4-Bromomethyl-2(1H)-quinolinone price4-Bromomethyl-2(1H)-quinolinone structure4-Bromomethyl-2(1H)-quinolinone SDSbuy 4-Bromomethyl-2(1H)-quinolinone4-Bromomethyl-2(1H)-quinolinone supplier4-Bromomethyl-2(1H)-quinolinone uses4-Bromomethyl-2(1H)-quinolinone molecular weightprice of 4-Bromomethyl-2(1H)-quinolinone4-Bromomethyl-2(1H)-quinolinone chemical name formula of 4-Bromomethyl-2(1H)-quinolinone
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label