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CS-W001157 4
Total: USD 88.00

(S)-1-(Naphthalen-2-yl)ethanamine

  • CAS No. 3082-62-0

  • Cat. No. CS-0053589
  • Purity≥97%
  • MDL No.MFCD00085366

*For research and further manufacturing use only, not for direct human use.

(S)-1-(Naphthalen-2-yl)ethanamine|CS-0053589

Structure of 3082-62-0

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General Information

  • CAS No. 3082-62-0
  • Cat. No. CS-0053589
  • Purity ≥97%
  • MDL No. MFCD00085366
  • Storage RT, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃N
  • Molecular Weight 171.24
  • Synonym(s) (S)-2-(1-Aminoethyl)naphthalene
  • SMILES C[C@H](N)C1=CC2=CC=CC=C2C=C1

Description

(S)-1-(Naphthalen-2-yl)ethanamine is a chiral amine featuring a naphthalene moiety attached to a stereodefined ethylamine side chain. This configuration imparts distinct stereochemical properties useful in asymmetric synthesis and ligand design. The molecule exhibits enhanced solubility in organic solvents and stability under standard bench conditions, enabling reliable use in catalytic systems and pharmaceutical intermediates.

Application

(S)-1-(Naphthalen-2-yl)ethanamine serves as a chiral building block for asymmetric synthesis, enabling the construction of biologically relevant scaffolds through enantioselective transformations. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate efficient access to pharmaceutically relevant amines. The molecule functions effectively in transition-metal-catalyzed couplings and serves as a key intermediate in the development of chiral ligands and active pharmaceutical ingredients.

Synthesis

  • Route1
    • 2-Acetonaphthone, ≥99%|CS-1268986
      93-08-3
    • ~%
    • In-stock
      (S)-1-(Naphthalen-2-yl)ethanamine|CS-0053589
      3082-62-0
    • 1-(Naphthalen-2-yl)ethanamine Cinacalcet Impurity|CS-0229380
      1201-74-7

    References

    • Journal of Molecular Structure, , vol. 475, # 2-3 p. 121 - 130
  • Route2
    • 1-(Naphthalen-2-yl)ethanamine Cinacalcet Impurity|CS-0229380
      1201-74-7
    • ~%
    • In-stock
      (S)-1-(Naphthalen-2-yl)ethanamine|CS-0053589
      3082-62-0
    • 1-(Naphthalen-2-yl)ethanamine Cinacalcet Impurity|CS-0229380
      1201-74-7

    References

    • Tetrahedron Asymmetry, , vol. 13, # 20 p. 2277 - 2282
  • Route3
    • 1-(Naphthalen-2-yl)ethanamine Cinacalcet Impurity|CS-0229380
      1201-74-7
    • null|null
      98-88-4
    • ~%
    • null|null
      114459-78-8
    • null|null
      3976-23-6
    • In-stock
      (S)-1-(Naphthalen-2-yl)ethanamine|CS-0053589
      3082-62-0
    • 1-(Naphthalen-2-yl)ethanamine Cinacalcet Impurity|CS-0229380
      1201-74-7

    References

    • Tetrahedron, , vol. 70, # 2 p. 197 - 203

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H315-H319-H335-H411
Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.8595
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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