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Structure of 4865-84-3
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This acetic acid derivative features a 1,2-benzisoxazole core that imparts high metabolic stability and enhanced membrane permeability. The para-positioned carboxylic acid group enables direct conjugation or derivatization in medicinal chemistry campaigns. The rigid heteroaromatic scaffold provides strong π-stacking potential, making it valuable for target engagement studies and probe development in chemical biology.
2-(1,2-Benzisoxazol-3-yl)acetic acid serves as a versatile building block for constructing bioactive heterocyclic scaffolds. Its carboxylic acid functionality enables direct amidation, esterification, or derivatization under standard conditions. The benzisoxazole core provides metabolic stability and favorable pharmacophoric properties, making it valuable in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses and scale-up processes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: