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CS-W001157 4
Total: USD 88.00

4-Quinolinecarboxylic acid

  • CAS No. 486-74-8

  • Cat. No. CS-0008340
  • Purity≥98%
  • MDL No.MFCD00006782

*For research and further manufacturing use only, not for direct human use.

4-Quinolinecarboxylic acid|CS-0008340

Structure of 486-74-8

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General Information

  • CAS No. 486-74-8
  • Cat. No. CS-0008340
  • Purity ≥98%
  • MDL No. MFCD00006782
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO₂
  • Molecular Weight 173.17
  • Synonym(s) Cinchoninic acid; 4-Carboxyquinoline; NSC 13138
  • SMILES O=C(C1=CC=NC2=CC=CC=C12)O

Description

4-Quinolinecarboxylic acid was used in the coupling reaction with diamine linker. A 4-quinolinecarboxylic acid analogue, brequinar sodium was used to inhibit dihydroorotate dehydrogenase and the de novo biosynthesis of pyrimidine.

Synthesis

  • Route1
    • null|null
      491-35-0
    • ~86%
    • In-stock
      4-Quinolinecarboxylic acid|CS-0008340
      486-74-8

    References

    • Sakaguchi, Satoshi; Shibamoto, Akihiro; Ishii, Yasutaka Chemical Communications, 2002 , # 2 p. 180 - 181
  • Route2

    References

    • Ainley; King Proceedings of the Royal Society of London, Series B: Biological Sciences, 1938 , vol. 125, p. 60,69
  • Route3
    • null|null
      5632-16-6
    • ~83%
    • In-stock
      4-Quinolinecarboxylic acid|CS-0008340
      486-74-8

    References

    • Zhong, Qi-Di; Xue, Yun-Zhou; Yan, Hong; Song, Xiu-Qing; Zhong, Ru-Gang Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 18 p. 5532 - 5535

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.933
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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