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CS-W001157 4
Total: USD 88.00

Quinoline-4-carbaldehyde

  • CAS No. 4363-93-3

  • Cat. No. CS-W007672
  • Purity≥96%
  • MDL No.MFCD00006781

*For research and further manufacturing use only, not for direct human use.

Quinoline-4-carbaldehyde|CS-W007672

Structure of 4363-93-3

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General Information

  • CAS No. 4363-93-3
  • Cat. No. CS-W007672
  • Purity ≥96%
  • MDL No. MFCD00006781
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO
  • Molecular Weight 157.17
  • Synonym(s) Cinchoninaldehyde
  • SMILES C1=CC=CC2=NC=CC(=C12)C=O

Description

4-Quinolinecarboxaldehyde(cinchoninaldehyde) was used in the synthesis of lepidylamines.

Application

Quinoline-4-carbaldehyde serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling direct incorporation of a quinoline scaffold with a reactive aldehyde handle. Its stability under standard bench conditions and compatibility with nucleophilic addition, reductive amination, and condensation reactions facilitate efficient construction of heterocyclic frameworks, drug candidates, and functionalized ligands.

Synthesis

  • Route1
    • null|null
      491-35-0
    • ~92%
    • In-stock
      Quinoline-4-carbaldehyde|CS-W007672
      4363-93-3

    References

    • Vismara, Elena; Fontana, Francesca; Minisci, Francesco Gazzetta Chimica Italiana, 1987 , vol. 117, # 2 p. 135 - 136
  • Route2
    • null|null
      5450-80-6
    • ~80%
    • In-stock
      Quinoline-4-carbaldehyde|CS-W007672
      4363-93-3

    References

    • Katritzky, A. R.; Chapman, A. V.; Dowlatshahi, H. M. Acta Chimica Academiae Scientiarum Hungaricae, 1981 , vol. 107, p. 315 - 320
  • Route3
    • null|null
      491-35-0
    • ~82%
    • In-stock
      Quinoline-4-carbaldehyde|CS-W007672
      4363-93-3
    • In-stock
      4-Quinolinecarboxylic acid|CS-0008340
      486-74-8

    References

    • Achremowicz, Lucjan Synthetic Communications, 1996 , vol. 26, # 9 p. 1681 - 1684

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.0473
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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