Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3,3-Dimethylglutaric acid

  • CAS No. 4839-46-7

  • Cat. No. CS-W008097
  • Purity≥98%
  • MDL No.MFCD00002716

*For research and further manufacturing use only, not for direct human use.

3,3-Dimethylglutaric acid|CS-W008097

Structure of 4839-46-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 4839-46-7
  • Cat. No. CS-W008097
  • Purity ≥98%
  • MDL No. MFCD00002716
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O₄
  • Molecular Weight 160.17
  • Synonym(s) None
  • SMILES O=C(O)CC(C)(C)CC(O)=O

Description

m-PEG5-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Application

3,3-Dimethylglutaric acid serves as a versatile building block in synthetic organic chemistry, offering enhanced steric bulk at the C3 position that influences reactivity in condensation and cyclization processes. Its stability under standard bench conditions and compatibility with common functional groups facilitate efficient synthesis of cyclic architectures, including heterocycles and bioactive scaffolds. The molecule functions effectively in esterification, amide coupling, and decarboxylation reactions, enabling access to structurally diverse intermediates for medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • 4,4-Dimethyl-2,6-dioxopiperidine-3,5-dicarbonitrile|CS-0366492
      61193-04-2
    • ~99%
    • In-stock
      3,3-Dimethylglutaric acid|CS-W008097
      4839-46-7

    References

    • Holder, Richard W.; Daub, John P.; Baker, Wesley E.; Gilbert, Raymond H; Graf, Norman A. Journal of Organic Chemistry, 1982 , vol. 47, # 8 p. 1445 - 1451
  • Route2

    References

    • Singh, Sundaram; Shukla, Ajay Kumar; Singh, Krishna Nand Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 10 p. 1184 - 1188
  • Route3

    References

    • Chang, Chih-Shiang; Lin, Ying-Ting; Shih, Shin-Ru; Lee, Chung-Chi; Lee, Yen-Chun; Tai, Chia-Liang; Tseng, Sung-Nien; Chern, Jyh-Haur Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3522 - 3535

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   74.6
  • LogP   0.962
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3,3-Dimethylglutaric acid sigma3,3-Dimethylglutaric acid manufacturer3,3-Dimethylglutaric acid price3,3-Dimethylglutaric acid structure3,3-Dimethylglutaric acid SDSbuy 3,3-Dimethylglutaric acid3,3-Dimethylglutaric acid supplier3,3-Dimethylglutaric acid uses3,3-Dimethylglutaric acid molecular weightprice of 3,3-Dimethylglutaric acid3,3-Dimethylglutaric acid chemical name formula of 3,3-Dimethylglutaric acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label