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CS-W001157 4
Total: USD 88.00

3,5-Dichloro-2-fluorobenzaldehyde

  • CAS No. 477535-42-5

  • Cat. No. CS-0093405
  • Purity≥97%
  • MDL No.MFCD26687657

*For research and further manufacturing use only, not for direct human use.

3,5-Dichloro-2-fluorobenzaldehyde|CS-0093405

Structure of 477535-42-5

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General Information

  • CAS No. 477535-42-5
  • Cat. No. CS-0093405
  • Purity ≥97%
  • MDL No. MFCD26687657
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃Cl₂FO
  • Molecular Weight 193.00
  • Synonym(s) None
  • SMILES O=CC1=CC(Cl)=CC(Cl)=C1F

Description

3,5-Dichloro-2-fluorobenzaldehyde features a fluorinated benzene ring bearing two chlorine substituents and a formyl group at the ortho position. This electron-deficient aromatic aldehyde integrates readily into cross-coupling reactions and serves as a key building block in pharmaceutical intermediates and agrochemical synthesis. The combination of halogenation and carbonyl functionality enables precise functionalization under mild conditions.

Application

3,5-Dichloro-2-fluorobenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of fluorinated aromatic scaffolds. Its electron-deficient aromatic ring facilitates nucleophilic substitution and coupling reactions, while the aldehyde group supports reductive amination, imine formation, and Grignard additions. Bench-stable and readily purified by distillation or chromatography, it functions reliably in multi-step syntheses requiring precise regiocontrol.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.945
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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