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CS-W001157 4
Total: USD 88.00

Colchiceine

  • CAS No. 477-27-0

  • Cat. No. CS-0094405
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Colchiceine|CS-0094405

Structure of 477-27-0

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General Information

  • CAS No. 477-27-0
  • Cat. No. CS-0094405
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₃NO₆
  • Molecular Weight 385.41
  • Synonym(s) O10-Demethylcolchicine
  • SMILES CC(N[C@H](C1=C2)CCC3=CC(OC)=C(OC)C(OC)=C3C1=CC=C(O)C2=O)=O

Synthesis

  • Route1
    • Trimethylcolchicinic acid|CS-0026198
      3482-37-9
    • null|null
      108-24-7
    • ~%
    • Colchiceine|CS-0094405
      477-27-0

    References

    • Roesner, Manfred; Capraro, Hans-Georg; Jacobson, Arthur E.; Atwell, Louise; Brossi, Arnold; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 257 - 261
  • Route2
    • null|null
      73307-44-5
    • ~%
    • Colchiceine|CS-0094405
      477-27-0

    References

    • Corrodi; Hardegger Helvetica Chimica Acta, 1957 , vol. 40, p. 193,198, 199
  • Route3
    • null|null
      102419-93-2
    • ~%
    • Colchiceine|CS-0094405
      477-27-0

    References

    • Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1544
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   94.09
  • LogP   2.5686
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   4

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