Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Boronic acid, B-(5-chloro-2-methoxy-4-pyridinyl)-

  • CAS No. 475275-69-5

  • Cat. No. CS-0030484
  • Purity≥90%
  • MDL No.MFCD06658398

*For research and further manufacturing use only, not for direct human use.

Boronic acid, B-(5-chloro-2-methoxy-4-pyridinyl)-|CS-0030484

Structure of 475275-69-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 475275-69-5
  • Cat. No. CS-0030484
  • Purity ≥90%
  • MDL No. MFCD06658398
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BClNO₃
  • Molecular Weight 187.39
  • Synonym(s) boronic acid, B-(5-chloro-2-methoxy-4-pyridinyl)-
  • SMILES COC1=NC=C(Cl)C(B(O)O)=C1

Description

5-Chloro-2-methoxypyridin-4-yl-4-boronic acid features a pyridine core functionalized with chlorine, methoxy, and boronic acid groups, enabling direct incorporation into Suzuki-Miyaura cross-coupling reactions. The electron-deficient arylboronate facilitates efficient C–C bond formation under mild conditions. This bench-stable reagent delivers high chemoselectivity in complex molecule synthesis.

Application

5-Chloro-2-methoxypyridin-4-yl-4-boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation with aryl and heteroaryl halides. The pyridine core provides orthogonal reactivity, while the methoxy group enhances solubility and modulates electronic properties. Bench-stable and readily purified by recrystallization, it facilitates scalable synthesis of functionalized pyridine scaffolds relevant to medicinal chemistry and agrochemical development.

Synthesis

  • Route1

    References

    • Parry, Paul R.; Wang, Changsheng; Batsanov, Andrei S.; Bryce, Martin R.; Tarbit, Brian Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7541 - 7543

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   62.58
  • LogP   -0.5766
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 475275-69-5 sigma475275-69-5 manufacturer475275-69-5 price475275-69-5 structure475275-69-5 SDSbuy 475275-69-5475275-69-5 supplier475275-69-5 uses475275-69-5 molecular weightprice of 475275-69-5475275-69-5 chemical name formula of 475275-69-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label