2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Name: 2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 475250-52-3
Cat. No. CS-0153821
Purity≥96%
MDL No.MFCD10698526

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0153821

Structure of 475250-52-3

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This boronate ester features a methoxy-substituted benzyl group that enhances solubility and stability in polar solvents. The tetramethyl-1,3,2-dioxaborolane core provides excellent shelf life and reactivity in Suzuki-Miyaura cross-coupling reactions under standard conditions.

Application

2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-friendly boron building block for Suzuki-Miyaura cross-coupling reactions. The methoxy-substituted benzyl group provides enhanced solubility and functional group tolerance, enabling efficient late-stage diversification in complex molecule synthesis. Its high reactivity and minimal protodeboronation under standard coupling conditions make it ideal for constructing biaryl and heteroaryl scaffolds in medicinal chemistry and materials science applications.

General Information

CAS No. 475250-52-3
Cat. No. CS-0153821
Purity ≥96%
MDL No. MFCD10698526
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₂₁BO₃
Molecular Weight 248.13
Synonym(s) 4-Methoxybenzylboronic Acid Pinacol Ester
SMILES CC1(C)C(C)(C)OB(CC2=CC=C(C=C2)OC)O1

Computational Chemistry Data

TPSA 27.69
LogP 2.8691
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Synthesis Organometallic Reagents Organoboron Boronic Acids and Derivatives

Key Words

475250-52-3 sigma475250-52-3 manufacturer475250-52-3 price475250-52-3 structure475250-52-3 SDSbuy 475250-52-3475250-52-3 supplier475250-52-3 uses475250-52-3 molecular weightprice of 475250-52-3475250-52-3 chemical name formula of 475250-52-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CAS No. 475250-52-3

Recommended Products