Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane

  • CAS No. 475250-46-5

  • Cat. No. CS-W006861
  • Molecule weight286.10
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane|CS-W006861

Structure of 475250-46-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 475250-46-5
  • Cat. No. CS-W006861
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈BF₃O₂
  • Molecular Weight 286.10
  • Synonym(s) 4,4,5,5-tetramethyl-2-[[4-(trifluoromethyl)phenyl]methyl]-1,3,2-dioxaborolane
  • SMILES CC1(C)OB(CC2=CC=C(C=C2)C(F)(F)F)OC1(C)C

Description

This boronate moiety features a sterically hindered tetramethyl-1,3,2-dioxaborolane ring paired with a para-trifluoromethylbenzyl substituent, delivering enhanced stability and solubility in organic media. The electron-deficient trifluoromethyl group improves reactivity in cross-coupling processes, enabling efficient C–C bond formation under standard conditions.

Application

4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethylbenzyl group imparts enhanced lipophilicity and metabolic stability, making it valuable for constructing biologically relevant scaffolds. Its tetramethyl-substituted dioxaborolane core ensures high chemical stability, excellent functional group tolerance, and compatibility with standard coupling conditions across diverse substrates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   18.46
  • LogP   3.8793
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 475250-46-5 sigma475250-46-5 manufacturer475250-46-5 price475250-46-5 structure475250-46-5 SDSbuy 475250-46-5475250-46-5 supplier475250-46-5 uses475250-46-5 molecular weightprice of 475250-46-5475250-46-5 chemical name formula of 475250-46-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label