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CS-W001157 4
Total: USD 88.00

Cbz-NH-PEG3-CH2COOH

  • CAS No. 462100-05-6

  • Cat. No. CS-0116274
  • Purity≥98%
  • MDL No.MFCD27978797

*For research and further manufacturing use only, not for direct human use.

Cbz-NH-PEG3-CH2COOH|CS-0116274

Structure of 462100-05-6

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General Information

  • CAS No. 462100-05-6
  • Cat. No. CS-0116274
  • Purity ≥98%
  • MDL No. MFCD27978797
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₃NO₇
  • Molecular Weight 341.36
  • Synonym(s) None
  • SMILES O=C(OCC1=CC=CC=C1)NCCOCCOCCOCC(O)=O

Description

Cbz-NH-PEG3-CH2COOH features a carbamoyl-protected amine linked to a triethylene glycol spacer terminating in a carboxylic acid. This bifunctional construct enables site-specific conjugation and bioconjugation workflows, offering enhanced solubility and stability under standard conditions.

Application

Cbz-NH-PEG3-CH2COOH serves as a versatile bifunctional linker for peptide and bioconjugation applications. The Cbz group provides reliable nitrogen protection, while the PEG3 spacer offers enhanced solubility and reduced aggregation. The terminal carboxylic acid enables efficient coupling via amide bond formation, facilitating synthesis of peptide-drug conjugates and functionalized biomolecules with excellent handling and purification characteristics.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   103.32
  • LogP   1.0472
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   13

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