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CS-W001157 4
Total: USD 88.00

N-Methylpyridin-2-amine

  • CAS No. 4597-87-9

  • Cat. No. CS-0134535
  • Purity≥96%
  • MDL No.MFCD00006250

*For research and further manufacturing use only, not for direct human use.

N-Methylpyridin-2-amine|CS-0134535

Structure of 4597-87-9

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General Information

  • CAS No. 4597-87-9
  • Cat. No. CS-0134535
  • Purity ≥96%
  • MDL No. MFCD00006250
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂
  • Molecular Weight 108.14
  • Synonym(s) 2-Methylaminopyridine
  • SMILES CNC1=NC=CC=C1

Description

N-Methylpyridin-2-amine offers a robust pyridine scaffold with enhanced nucleophilicity due to the N-methyl substitution, enabling efficient coupling in transition-metal catalysis. This bench-stable heterocycle integrates readily into pharmaceutical intermediates and ligand design, where its electron-rich nitrogen facilitates coordination to metal centers.

Synthesis

  • Route1
    • null|null
      125867-09-6
    • ~95%
    • In-stock
      N-Methylpyridin-2-amine|CS-0134535
      4597-87-9

    References

    • Shewalkar, Mukesh P.; Rao, Ramakrishna R.; Reddy, Veerbhadra; Darandale, Sunil N.; Shinde, Devanand B. Letters in Organic Chemistry, 2013 , vol. 10, # 1 p. 60 - 64
  • Route2

    References

    • Zhang, En-Xuan; Wang, De-Xian; Zheng, Qi-Yu; Wang, Mei-Xiang Organic Letters, 2008 , vol. 10, # 12 p. 2565 - 2568
  • Route3
    • null|null
      694-59-7
    • null|null
      74-89-5
    • ~82%
    • In-stock
      N-Methylpyridin-2-amine|CS-0134535
      4597-87-9

    References

    • Londregan, Allyn T.; Jennings, Sandra; Wei, Liuqing Organic Letters, 2010 , vol. 12, # 22 p. 5254 - 5257

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H302+H312+H332-H315-H319-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   1.1233
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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