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CS-W001157 4
Total: USD 88.00

(2-Bromopyridin-4-yl)boronic acid

  • CAS No. 458532-94-0

  • Cat. No. CS-W015534
  • Purity≥98%
  • MDL No.MFCD06798244

*For research and further manufacturing use only, not for direct human use.

(2-Bromopyridin-4-yl)boronic acid|CS-W015534

Structure of 458532-94-0

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General Information

  • CAS No. 458532-94-0
  • Cat. No. CS-W015534
  • Purity ≥98%
  • MDL No. MFCD06798244
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BBrNO₂
  • Molecular Weight 201.81
  • Synonym(s) 2-Bromopyridine-4-boronic acid
  • SMILES OB(O)C1=CC(Br)=NC=C1

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized pyridyl architectures with high fidelity. The bromopyridine handle enables sequential diversification, while the bench-stable boronic acid group ensures reliable performance in iterative synthesis workflows.

Application

(2-Bromopyridin-4-yl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. Its boronic acid functionality offers good bench stability and compatibility with diverse reaction conditions, while the pyridine ring provides orthogonal reactivity for further functionalization. This compound facilitates the construction of biaryl scaffolds commonly found in pharmaceutical intermediates and agrochemicals.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.4761
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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