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Structure of 458-11-7
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N-(3,4-Difluorophenyl)acetamide features a difluorinated aromatic ring that imparts enhanced metabolic stability and lipophilicity, enabling efficient integration into bioactive scaffolds. The amide linkage provides structural rigidity and hydrogen-bonding capacity, supporting target engagement in medicinal chemistry applications.
N-(3,4-Difluorophenyl)acetamide serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through standard amide coupling and electrophilic substitution reactions. Its difluorophenyl motif enhances metabolic stability and modulates lipophilicity, while the acetamide group offers reliable functionalization and purification advantages. Bench-stable and compatible with diverse reaction conditions, it functions effectively in multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: