Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

H-Glu(OBzl)-OBzl.HCl

  • CAS No. 4561-10-8

  • Cat. No. CS-W018863
  • Purity≥97%
  • MDL No.MFCD00035103

*For research and further manufacturing use only, not for direct human use.

H-Glu(OBzl)-OBzl.HCl|CS-W018863

Structure of 4561-10-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 4561-10-8
  • Cat. No. CS-W018863
  • Purity ≥97%
  • MDL No. MFCD00035103
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₂ClNO₄
  • Molecular Weight 363.84
  • Synonym(s) None
  • SMILES O=C(OCC1=CC=CC=C1)[C@@H](N)CCC(OCC2=CC=CC=C2)=O.[H]Cl

Description

H-Glu(OBzl)-OBzl.HCl features a protected glutamic acid residue with benzyl ester groups at both carboxylic acid sites, enabling stable incorporation into peptide chains. The hydrochloride salt enhances solubility and handling under standard bench conditions. This derivative serves as a key building block for synthesizing bioactive peptides requiring side-chain protection.

Application

H-Glu(OBzl)-OBzl·HCl serves as a well-established, bench-stable building block for the synthesis of peptide-based pharmaceutical intermediates. The dibenzyl ester protection provides orthogonal stability under standard peptide coupling conditions, enabling selective deprotection and efficient incorporation into complex sequences. Its defined stereochemistry and compatibility with common activation protocols facilitate reliable use in solid-phase and solution-phase synthesis workflows.

Synthesis

  • Route1

    References

    • You, Jun; Liu, Bo; Wang, Yi Journal of the Chinese Chemical Society, 2009 , vol. 56, # 5 p. 1010 - 1017

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   78.62
  • LogP   3.0025
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   8

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • H-Glu(OBzl)-OBzl.HCl sigmaH-Glu(OBzl)-OBzl.HCl manufacturerH-Glu(OBzl)-OBzl.HCl priceH-Glu(OBzl)-OBzl.HCl structureH-Glu(OBzl)-OBzl.HCl SDSbuy H-Glu(OBzl)-OBzl.HClH-Glu(OBzl)-OBzl.HCl supplierH-Glu(OBzl)-OBzl.HCl usesH-Glu(OBzl)-OBzl.HCl molecular weightprice of H-Glu(OBzl)-OBzl.HClH-Glu(OBzl)-OBzl.HCl chemical name formula of H-Glu(OBzl)-OBzl.HCl
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label