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CS-W001157 4
Total: USD 88.00

(S)-2-aminopentanedioic acid hydrochloride

  • CAS No. 138-15-8

  • Cat. No. CS-W017035
  • Purity≥98%
  • MDL No.MFCD00012619

*For research and further manufacturing use only, not for direct human use.

(S)-2-aminopentanedioic acid hydrochloride|CS-W017035

Structure of 138-15-8

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General Information

  • CAS No. 138-15-8
  • Cat. No. CS-W017035
  • Purity ≥98%
  • MDL No. MFCD00012619
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀ClNO₄
  • Molecular Weight 183.59
  • Synonym(s) None
  • SMILES OC(CC[C@H](N)C(O)=O)=O.Cl

Description

Phenylboronic acid is a highly stable receptor ligand used in cross-coupling reactions and drug delivery.Phenylboronic acid (PBA) is an organoboronic acid. It behaves as a molecular receptor that can attach to compounds containing cis-diol group. Microwave-assisted Suzuki coupling of aryl chlorides with phenylboronic acid in the presence of Pd/C (catalyst) and water (solvent) has been described. Palladium-catalyzed cross-coupling reaction of phenylboronicacid with haloarenes to afford biaryls has been reported.Phenylboronic acid may be employed in the following reactions:Rhodium-catalyzed intramolecular amination. Pd-catalyzed direct arylation. Mizoroki-Heck and Suzuki-Miyaura coupling reactions catalyzed by palladium nanoparticles. Palladium-catalyzed stereoselective Heck-type reaction. Highly effective Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water. Phenylboronic acid may be employed as reagent in the preparation of:Ni(II) pincer complex and Pd(II) pyridoxal hydrazone metallacycles as catalysts for the Suzuki-Miyaura cross-coupling reactions.N-type polymers for all-polymer solar cells. Novel series of potent and selective mTOR kinase inhibitors. Inhibitors of lactate dehydrogenase against cancer cell proliferation.

Synthesis

  • Route1
    • null|null
      2709-66-2
    • ~89%
    • In-stock
      (S)-2-aminopentanedioic acid hydrochloride|CS-W017035
      138-15-8

    References

    • Field, Steven J.; Young, Douglas W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 10 p. 2387 - 2392
  • Route2

    References

    • Chemical & Pharmaceutical Bulletin, , vol. 28, # 5 p. 1449 - 1458
  • Route3

    References

    • Chemical & Pharmaceutical Bulletin, , vol. 28, # 5 p. 1449 - 1458

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.62
  • LogP   -0.3151
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   4

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