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Structure of 455957-94-5
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This pyrrolidine derivative features a tert-butyl group at the nitrogen and a sterically hindered 2,4-difluorophenyl moiety, enhancing metabolic stability. The (3S,4R) stereochemistry ensures optimal spatial alignment for target engagement, while the carboxylic acid facilitates conjugation in bioactive molecule design. Bench-stable and moisture-tolerant, it integrates efficiently into peptide-based scaffolds and drug discovery campaigns.
(3S,4R)-1-(tert-Butyl)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid serves as a conformationally constrained chiral building block for medicinal chemistry applications. Its rigid pyrrolidine core, combined with orthogonal functional groups, enables efficient access to bioactive heterocycles. The tert-butyl group enhances bench stability and simplifies purification, while the 2,4-difluorophenyl moiety provides favorable metabolic properties and targeted binding interactions in CNS-targeted drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: