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Structure of 4537-73-9
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Pyrimidine-2-carbothioamide features a thiocarbonyl group directly attached to the pyrimidine ring, delivering enhanced reactivity in nucleophilic substitution and coordination chemistry. This scaffold integrates readily into heterocyclic frameworks, offering robust stability under standard conditions while enabling efficient functionalization at the C2 position.
Pyrimidine-2-carbothioamide serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds through nucleophilic substitution and condensation reactions. Its thiocarbonyl group exhibits predictable reactivity in transition-metal-catalyzed couplings and cyclization processes, offering robust functional group tolerance. The compound demonstrates excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: