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CS-W001157 4
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2-Chloro-N-methylethanamine hydrochloride

  • CAS No. 4535-90-4

  • Cat. No. CS-W019383
  • Purity≥97%
  • MDL No.MFCD00050517

*For research and further manufacturing use only, not for direct human use.

2-Chloro-N-methylethanamine hydrochloride|CS-W019383

Structure of 4535-90-4

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General Information

  • CAS No. 4535-90-4
  • Cat. No. CS-W019383
  • Purity ≥97%
  • MDL No. MFCD00050517
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₉Cl₂N
  • Molecular Weight 130.02
  • Synonym(s) None
  • SMILES ClCCNC.Cl

Description

This hydrochloride salt delivers a reactive chloroethylamine moiety for nucleophilic substitution, enabling efficient incorporation into bioconjugates and pharmaceutical intermediates. The methylation enhances solubility and stability under standard conditions, while the chloride group provides a robust leaving group for downstream functionalization.

Synthesis

  • Route1

    References

    • University of Rochester Patent: US5233031 A1, 1993 ;
  • Route2

    References

    • CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin Patent: WO2013/97773 A1, 2013 ; Location in patent: Paragraph 0236; 0312 ;
  • Route3
    • null|null
      1072-44-2
    • ~%
    • In-stock
      2-Chloro-N-methylethanamine hydrochloride|CS-W019383
      4535-90-4

    References

    • Marckwald; Frobenius Chemische Berichte, 1901 , vol. 34, p. 3549

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   0.8664
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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