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CS-W001157 4
Total: USD 88.00

4-(4-Methoxyphenyl)butanoic acid

  • CAS No. 4521-28-2

  • Cat. No. CS-W022000
  • Purity≥97%
  • MDL No.MFCD00004404

*For research and further manufacturing use only, not for direct human use.

4-(4-Methoxyphenyl)butanoic acid|CS-W022000

Structure of 4521-28-2

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General Information

  • CAS No. 4521-28-2
  • Cat. No. CS-W022000
  • Purity ≥97%
  • MDL No. MFCD00004404
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄O₃
  • Molecular Weight 194.23
  • Synonym(s) 4-(4-Methoxyphenyl)butyric acid
  • SMILES O=C(O)CCCC1=CC=C(OC)C=C1

Description

4-(4-Methoxyphenyl)butanoic acid features a conjugated aryl-alkyl linker with a terminal carboxylic acid, enabling direct integration into amide coupling workflows. The para-methoxy substituent enhances solubility and electron-donating character, while the aliphatic chain offers conformational flexibility for molecular scaffold design.

Application

4-(4-Methoxyphenyl)butanoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling the construction of biologically relevant arylalkyl scaffolds. Its robust functionality—combining a stable aromatic ring with a linear aliphatic chain bearing a carboxylic acid—facilitates diverse transformations including esterification, amidation, and decarboxylation. The molecule exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.1025
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   5

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