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CS-W001157 4
Total: USD 88.00

4-(4-Hydroxyphenyl)butanoic acid

  • CAS No. 7021-11-6

  • Cat. No. CS-W019452
  • Purity≥98%
  • MDL No.MFCD00033287

*For research and further manufacturing use only, not for direct human use.

4-(4-Hydroxyphenyl)butanoic acid|CS-W019452

Structure of 7021-11-6

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General Information

  • CAS No. 7021-11-6
  • Cat. No. CS-W019452
  • Purity ≥98%
  • MDL No. MFCD00033287
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₃
  • Molecular Weight 180.20
  • Synonym(s) None
  • SMILES O=C(O)CCCC1=CC=C(O)C=C1

Description

4-(4-Hydroxyphenyl)butanoic acid features a hydroxylated aromatic ring linked via a four-carbon aliphatic chain to a carboxylic acid group. This structure combines phenolic reactivity with flexible backbone chemistry, enabling integration into bioconjugation strategies and polymer architectures. The molecule exhibits enhanced solubility in polar solvents and stability under standard bench conditions.

Application

4-(4-Hydroxyphenyl)butanoic acid serves as a versatile building block for synthesizing bioactive compounds and functional polymers. Its phenolic hydroxyl group enables facile derivatization, while the aliphatic carboxylic acid facilitates amide, ester, or coupling reactions under standard conditions. The molecule exhibits good bench stability and is readily purified by recrystallization, making it suitable for iterative synthetic workflows in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • Chu, Lin; Hutchins, Jennifer E.; Weber, Ann E.; Lo, Jane-Ling; Yang, Yi-Tien; Cheng, Kang; Smith, Roy G.; Fisher, Michael H.; Wyvratt, Matthew J.; Goulet, Mark T. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 509 - 513
  • Route2

    References

    • Panda, Atulya Kumar Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 2 p. 372 - 375
  • Route3
    • 4-(4-hydroxyphenyl)-4-oxobutanoic acid|CS-W000648
      56872-39-0
    • ~%
    • In-stock
      4-(4-Hydroxyphenyl)butanoic acid|CS-W019452
      7021-11-6

    References

    • Journal of the American Chemical Society, , vol. 81, p. 871,872

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.7995
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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