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CS-W001157 4
Total: USD 88.00

4-(p-tolyl)Butanoic acid

  • CAS No. 4521-22-6

  • Cat. No. CS-W002126
  • Purity≥98%
  • MDL No.MFCD00021786

*For research and further manufacturing use only, not for direct human use.

4-(p-tolyl)Butanoic acid|CS-W002126

Structure of 4521-22-6

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General Information

  • CAS No. 4521-22-6
  • Cat. No. CS-W002126
  • Purity ≥98%
  • MDL No. MFCD00021786
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄O₂
  • Molecular Weight 178.23
  • Synonym(s) 4-p-tolylbutyric acid
  • SMILES O=C(O)CCCC1=CC=C(C)C=C1

Description

4-(p-Tolyl)butanoic acid features a para-tolyl group appended to a butanoic acid chain, delivering a hydrophobic aromatic moiety paired with a carboxylic acid handle. This structure enables integration into bioconjugation workflows and serves as a key building block in medicinal chemistry for modulating lipophilicity and metabolic stability.

Application

4-(p-Tolyl)butanoic acid serves as a versatile building block in medicinal chemistry and materials science, enabling the synthesis of bioactive molecules and functional polymers. Its para-tolyl group provides steric and electronic modulation, while the carboxylic acid functionality facilitates amidation, esterification, and coupling reactions. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for scalable synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.40232
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

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