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CS-W001157 4
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Rivaroxaban impurity 41

  • CAS No. 446292-04-2

  • Cat. No. CS-0229654
  • Molecule weight222.20
  • Purity≥98%
  • MDL No.MFCD08236741

*For research and further manufacturing use only, not for direct human use.

Rivaroxaban impurity 41|CS-0229654

Structure of 446292-04-2

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General Information

  • CAS No. 446292-04-2
  • Cat. No. CS-0229654
  • Purity ≥98%
  • MDL No. MFCD08236741
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀N₂O₄
  • Molecular Weight 222.20
  • Synonym(s) None
  • SMILES O=C1N(CCOC1)C2=CC=C([N+]([O-])=O)C=C2

Synthesis

  • Route1

    References

    • ENANTIA, S.L.; RAFECAS JANE, Llorenc; COMELY, Alexander Christian; FERRALI, Alessandro; AMELA CORTES, Celia; PASTO AGUILA, Mireia Patent: WO2011/80341 A1, 2011 ; Location in patent: Page/Page column 15 ;
  • Route2

    References

    • MERCK PATENT GMBH Patent: WO2006/34789 A1, 2006 ; Location in patent: Page/Page column 41 ;
  • Route3

    References

    • GALAPAGOS NV; MENET, Christel Jeanne Marie; BLANC, Javier; JOUANNIGOT, Nolwenn; HODGES, Alastair James; VAN ROMPAEY, Luc Juliaan Corina; FLETCHER, Stephen Robert Patent: WO2010/10189 A1, 2010 ; Location in patent: Page/Page column 55 ; WO 2010/010189 A1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.68
  • LogP   0.958
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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