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CS-W001157 4
Total: USD 88.00

2,4-Difluoro-1-nitrobenzene

  • CAS No. 446-35-5

  • Cat. No. CS-W020034
  • Purity≥98%
  • MDL No.MFCD00007050

*For research and further manufacturing use only, not for direct human use.

2,4-Difluoro-1-nitrobenzene|CS-W020034

Structure of 446-35-5

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General Information

  • CAS No. 446-35-5
  • Cat. No. CS-W020034
  • Purity ≥98%
  • MDL No. MFCD00007050
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃F₂NO₂
  • Molecular Weight 159.09
  • Synonym(s) 2,4-Difluoronitrobenzene; NSC 10259; 2,4-Difluronitrobenzene
  • SMILES FC1=CC(F)=CC=C1[N+]([O-])=O

Description

Nucleophilic aromatic substitution of 2,4-difluoronitrobenzene with morpholine has been investigated using flow reactor with simulated moving bed (SMB) chromatography module.2,4-Difluoronitrobenzene has been used in the synthesis of:2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction()-horsfilineresin-bound 2-arylaminobenzimidazoles

Synthesis

  • Route1
    • null|null
      611-06-3
    • ~99%
    • In-stock
      2,4-Difluoro-1-nitrobenzene|CS-W020034
      446-35-5

    References

    • Fan, Ao; Chuah, Gaik-Khuan; Jaenicke, Stephan Catalysis Today, 2012 , vol. 198, # 1 p. 300 - 304
  • Route2

    References

    • Sasson, Yoel; Negussie, Samuel; Royz, Michael; Mushkin, Noam Chemical Communications, 1996 , # 3 p. 297 - 298
  • Route3
    • null|null
      611-06-3
    • ~68%
    • In-stock
      2-Chloro-4-fluoronitrobenzene|CS-W003054
      2106-50-5
    • In-stock
      2,4-Difluoro-1-nitrobenzene|CS-W020034
      446-35-5

    References

    • Lacour, Marie-Agnes; Zablocka, Maria; Duhayon, Carine; Majoral, Jean-Pierre; Taillefer, Marc Advanced Synthesis and Catalysis, 2008 , vol. 350, # 17 p. 2677 - 2682

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H227-H301-H315-H319-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   43.14
  • LogP   1.873
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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