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CS-W001157 4
Total: USD 88.00

2-Amino-4-fluorobenzoic acid Afatinib Impurity

  • CAS No. 446-32-2

  • Cat. No. CS-0167288
  • Purity≥98%
  • MDL No.MFCD00075553

*For research and further manufacturing use only, not for direct human use.

2-Amino-4-fluorobenzoic acid Afatinib Impurity|CS-0167288

Structure of 446-32-2

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General Information

  • CAS No. 446-32-2
  • Cat. No. CS-0167288
  • Purity ≥98%
  • MDL No. MFCD00075553
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆FNO₂
  • Molecular Weight None
  • Synonym(s) BUTTPARK 15\04-96
  • SMILES O=C(C1=CC=C(C=C1N)F)O

Synthesis

  • Route1

    References

    • Uchikawa, Osamu; Mitsui, Keita; Asakawa, Akiko; Morimoto, Shigeru; Yamamoto, Masataka; Kimura, Hiroyuki; Moriya, Takeo; Mizuno, Masahiro Patent: US2003/187014 A1, 2003 ;
  • Route2

    References

    • MITENI S.p.A. Patent: WO2003/95417 A1, 2003 ; Location in patent: Page/Page column 7 ;
  • Route3

    References

    • Riedel-de Haen Aktiengesellschaft Patent: US5744638 A1, 1998 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.1061
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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