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CS-W001157 4
Total: USD 88.00

Ethyl 2-amino-4-fluorobenzoate

  • CAS No. 117324-05-7

  • Cat. No. CS-W022651
  • Purity≥98%
  • MDL No.MFCD08275015

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-amino-4-fluorobenzoate|CS-W022651

Structure of 117324-05-7

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General Information

  • CAS No. 117324-05-7
  • Cat. No. CS-W022651
  • Purity ≥98%
  • MDL No. MFCD08275015
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀FNO₂
  • Molecular Weight 183.18
  • Synonym(s) ethyl-2-amino-4-fluorobenzoate
  • SMILES O=C(OCC)C1=CC=C(F)C=C1N

Synthesis

  • Route1
    • 2-Amino-4-fluorobenzoic acid Afatinib Impurity|CS-0167288
      446-32-2
    • ~95%
    • Ethyl 2-amino-4-fluorobenzoate|CS-W022651
      117324-05-7

    References

    • Portola Pharmaceuticals, Inc. Patent: US6906063 B2, 2005 ;
  • Route2
    • null|null
      64-17-5
    • 2-Amino-4-fluorobenzoic acid Afatinib Impurity|CS-0167288
      446-32-2
    • ~82%
    • Ethyl 2-amino-4-fluorobenzoate|CS-W022651
      117324-05-7

    References

    • Pandey, Anjali; Volkots, Deborah L.; Seroogy, Joseph M.; Rose, Jack W.; Yu, Jin-Chen; Lambing, Joseph L.; Hutchaleelaha, Athiwat; Hollenbach, Stanley J.; Abe, Keith; Giese, Neill A.; Scarborough, Robert M. Journal of Medicinal Chemistry, 2002 , vol. 45, # 17 p. 3772 - 3793
  • Route3

    References

    • Pfizer Inc. Patent: US4762838 A1, 1988 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.5846
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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