Lot numbers can be found on the outside label of a product:
Please log in for operation!
*For research and further manufacturing use only, not for direct human use.
Structure of 446-26-4
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Methyl 2-fluoropyridine-3-carboxylate features a fluorinated pyridine core with a strategically positioned ester group, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient ring facilitates nucleophilic substitution, while the methyl ester serves as a versatile handle for downstream functionalization. This compound exhibits excellent stability under standard conditions and is compatible with common coupling reactions in medicinal chemistry workflows.
Methyl 2-fluoropyridine-3-carboxylate serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions at the C2 position due to the ortho-fluoro activation. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient synthesis of functionalized pyridine derivatives. The ester group provides a handle for further derivatization, while the fluorine substituent enhances metabolic stability and modulates electronic properties in target molecules.
|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Lot numbers can be found on the outside label of a product: