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CS-W001157 4
Total: USD 88.00

2'-Fluoroacetophenone

  • CAS No. 445-27-2

  • Cat. No. CS-W020096
  • Purity≥97%
  • MDL No.MFCD00000320

*For research and further manufacturing use only, not for direct human use.

2'-Fluoroacetophenone|CS-W020096

Structure of 445-27-2

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General Information

  • CAS No. 445-27-2
  • Cat. No. CS-W020096
  • Purity ≥97%
  • MDL No. MFCD00000320
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇FO
  • Molecular Weight 138.14
  • Synonym(s) None
  • SMILES CC(C1=CC=CC=C1F)=O

Description

2'-Fluoroacetophenone features a fluorinated aromatic ring paired with a reactive ketone group, enabling selective electrophilic functionalization. This bench-stable compound integrates readily into synthetic routes requiring electron-deficient aryl motifs, particularly in pharmaceutical intermediates and agrochemical development.

Synthesis

  • Route1

    References

    • Wang, Qingfu; Du, Wangming; Liu, Tingting; Chai, Huining; Yu, Zhengkun Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1585 - 1588
  • Route2
    • null|null
      839721-38-9
    • ~%
    • In-stock
      2'-Fluoroacetophenone|CS-W020096
      445-27-2

    References

    • Hyder, Zeynab; Ruan, Jiwu; Xiao, Jianliang Chemistry - A European Journal, 2008 , vol. 14, # 18 p. 5555 - 5566
  • Route3
    • In-stock
      1-Bromo-2-fluorobenzene|CS-B1543
      1072-85-1
    • null|null
      111-34-2
    • ~83%
    • In-stock
      2'-Fluoroacetophenone|CS-W020096
      445-27-2

    References

    • Mo, Jun; Liu, Shifang; Xiao, Jianliang Tetrahedron, 2005 , vol. 61, # 41 p. 9902 - 9907

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P302+P352-P362-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.0283
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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