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CS-W001157 4
Total: USD 88.00

4-Cyclohexylbutanoic acid

  • CAS No. 4441-63-8

  • Cat. No. CS-0155329
  • Purity≥97%
  • MDL No.MFCD00001529

*For research and further manufacturing use only, not for direct human use.

4-Cyclohexylbutanoic acid|CS-0155329

Structure of 4441-63-8

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General Information

  • CAS No. 4441-63-8
  • Cat. No. CS-0155329
  • Purity ≥97%
  • MDL No. MFCD00001529
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈O₂
  • Molecular Weight 170.25
  • Synonym(s) None
  • SMILES C1CCC(CC1)CCCC(=O)O

Description

Cyclohexanebutyric acid was used in the growth of Arthrobacter sp. strain CA1. It was also used in the production of polyhydroxyalkanoates (PHAs).

Application

4-Cyclohexylbutanoic acid serves as a versatile building block in medicinal chemistry and materials science, enabling the synthesis of bioactive molecules and functional polymers. Its aliphatic chain with a cyclohexyl substituent provides favorable lipophilicity and steric bulk, enhancing membrane permeability in drug candidates. The carboxylic acid group facilitates straightforward derivatization—via amide formation, esterification, or activation for coupling reactions—while the structure exhibits good bench stability and ease of purification.

Synthesis

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      4-Cyclohexylbutanoic acid|CS-0155329
      4441-63-8

    References

    • Dow Chem. Co. Patent: US1961623 , 1933 ;
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      108-94-1
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      4-Cyclohexylbutanoic acid|CS-0155329
      4441-63-8

    References

    • Cairns; Joyce; Schreiber Journal of the American Chemical Society, 1948 , vol. 70, p. 1689
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      100053-57-4
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      4-Cyclohexylbutanoic acid|CS-0155329
      4441-63-8

    References

    • Detert, H.; Hagelueken, A.; Seifert, R.; Schunack, W. European Journal of Medicinal Chemistry, 1995 , vol. 30, # 4 p. 271 - 276

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.8216
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

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