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Structure of 4424-20-8
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This tetrahydrobenzazepine scaffold delivers a rigid, electron-rich aromatic core ideal for medicinal chemistry applications. Featuring a fully saturated seven-membered ring fused to benzene, it provides structural stability and enhanced metabolic resistance. The planar geometry facilitates π-stacking interactions in target binding sites, enabling efficient incorporation into CNS-active compounds.
2,3,4,5-Tetrahydro-1H-3-benzazepine serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization at the nitrogen and aromatic positions. Its stable, partially saturated ring system offers favorable handling characteristics and compatibility with common coupling reactions, facilitating rapid analog generation for target-directed synthesis.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: