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CS-W001157 4
Total: USD 88.00

Cyclobutanemethanol

  • CAS No. 4415-82-1

  • Cat. No. CS-W001922
  • Purity≥98%
  • MDL No.MFCD00001330

*For research and further manufacturing use only, not for direct human use.

Cyclobutanemethanol|CS-W001922

Structure of 4415-82-1

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General Information

  • CAS No. 4415-82-1
  • Cat. No. CS-W001922
  • Purity ≥98%
  • MDL No. MFCD00001330
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O
  • Molecular Weight 86.13
  • Synonym(s) Hydroxymethylcyclobutane; Cyclobutanemethanol
  • SMILES OCC1CCC1

Description

Cyclobutanemethanol features a rigid cyclobutane ring fused to a primary alcohol group, offering unique stereochemical constraints for synthetic applications. This bench-stable compound integrates readily into functionalized intermediates, enabling precise control in cyclic system elaboration and catalytic transformations under standard conditions.

Application

Cyclobutanemethanol serves as a valuable synthetic building block for strained ring systems and bioactive heterocycles. Its functional group enables straightforward derivatization via oxidation, substitution, or coupling reactions, while the cyclobutane scaffold imparts conformational rigidity useful in medicinal chemistry. The compound exhibits good bench stability and is compatible with standard purification methods, facilitating its use in multi-step syntheses and process development workflows.

Synthesis

  • Route1

    References

    • Toeroek, Bela; Molnar, Arpad Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 7 p. 801 - 804
  • Route2
    • Methyl cyclobut-1-ene-1-carboxylate|CS-0039950
      40628-41-9
    • ~%
    • In-stock
      Cyclobutanemethanol|CS-W001922
      4415-82-1
    • Cyclobut-1-en-1-ylmethanol|CS-1159980
      89182-08-1

    References

    • Griffin; Arris; Bleasdale; Boyle; Calvert; Curtin; Dalby; Kanugula; Lembicz; Newell; Pegg; Golding Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4071 - 4083
  • Route3

    References

    • Griffin; Arris; Bleasdale; Boyle; Calvert; Curtin; Dalby; Kanugula; Lembicz; Newell; Pegg; Golding Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4071 - 4083

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1987
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   0.7788
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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