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Structure of 441297-78-5
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This bicyclic lactam features a rigid, stereocontrolled framework ideal for asymmetric synthesis. The tert-butyl ester group enhances solubility and stability, while the oxo function at C1 provides a reactive handle for selective transformations. Bench-stable and moisture-tolerant, it serves as a key intermediate in complex heterocycle construction.
(3aR,7aR)-rel-tert-Butyl 1-oxohexahydrofuro[3,4-c]pyridine-5(3H)-carboxylate serves as a stereochemically defined intermediate for the construction of nitrogen-containing heterocycles. The oxo functionality at C1 enables selective reductions and nucleophilic additions, while the tert-butyl ester group provides stability and facilitates purification. Its rigid fused ring system offers predictable reactivity in transition-metal-catalyzed couplings and functional group interconversions, making it a valuable building block for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: