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CS-W001157 4
Total: USD 88.00

Phosphonoacetic acid

  • CAS No. 4408-78-0

  • Cat. No. CS-0102536
  • Molecule weight140.03
  • Purity≥98%
  • MDL No.MFCD00004311

*For research and further manufacturing use only, not for direct human use.

Phosphonoacetic acid|CS-0102536

Structure of 4408-78-0

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General Information

  • CAS No. 4408-78-0
  • Cat. No. CS-0102536
  • Purity ≥98%
  • MDL No. MFCD00004311
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₅O₅P
  • Molecular Weight 140.03
  • Synonym(s) None
  • SMILES O=C(O)CP(O)(O)=O

Description

Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts. It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase in vitro.Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells. It was also used as a phosphorus source for microbial growth in phosphate-independent manner.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   94.83
  • LogP   -0.7513
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   2

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